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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis of A375 using 83629-1-RR (same clone as 83629-1-PBS)

    WB analysis of A375 using 83629-1-RR (same clone as 83629-1-PBS)

    A375 cells were subjected to SDS PAGE followed by western blot with 83629-1-RR (CTHRC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83629-1-PBS in a different storage buffer formulation.

  • FC experiment of A375 using 83629-1-RR (same clone as 83629-1-PBS)

    FC experiment of A375 using 83629-1-RR (same clone as 83629-1-PBS)

    1x10^6 A375 cells were intracellularly stained with 0.25 ug CTHRC1 Recombinant antibody (83629-1-RR, Clone:240442E1) and APC-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF00011). This data was developed using the same antibody clone with 83629-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83629-1-RR

    Affinity and Kinetic Characterization of 83629-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83629-1-RR against Human CTHRC1 were performed. The affinity constant is 72.9 pM.

    {{ptg:ProductFeaturesInfo}}

CTHRC1 Recombinant monoclonal antibody, PBS Only

CTHRC1 Uni-rAb® Recombinant Antibody for WB, FC (Intra), ELISA
Cat No. 83629-1-PBS

产品说明书

CloneNo. 240442E1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, FC (Intra), ELISA

别名

UNQ762/PRO1550, Protein NMTC1, Collagen triple helix repeat-containing protein 1, collagen triple helix repeat containing 1, 240442E1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83629-1-PBS targets CTHRC1 in WB, FC (Intra), ELISA applications and shows reactivity with human samples.

经测试应用 WB, FC (Intra), ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag9812

Product name: Recombinant human CTHRC1 protein

Source: e coli.-derived, T-HIS

Tag: 6*His

Domain: 1-243 aa of BC014245

Sequence: MRPQGPAASPQRLRGLLLLLLLQLPAPSSASEIPKGKQKAQLRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQGSPEMNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSRIIIEELPK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 collagen triple helix repeat containing 1
别名 UNQ762/PRO1550, Protein NMTC1, Collagen triple helix repeat-containing protein 1, collagen triple helix repeat containing 1, 240442E1
计算分子量 243 aa, 26 kDa
观测分子量 25 kDa
GenBank蛋白编号BC014245
基因名称 CTHRC1
Gene ID (NCBI) 115908
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ96CG8
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Collagen triple helix repeat-containing protein 1 (CTHRC1), also known as protein NMTC1, is a glycosylated secreted protein. CTHRC1 was identified as a novel molecular in injured and diseased arteries where it may contribute to vascular remodeling by limiting collagen matrix deposition and promoting cell migration (PMID: 15618538). It has been reported that CTHRC1 is a positive regulator of osteoblastic bone formation (PMID: 18779865). Besides, studies reveal that CTHRC1 expression is implicated in various malignancies, including hepatocellular carcinoma, gastric carcinoma, colon cancer, and lung cancer (PMID: 23922981; 24504172; 24746208; 25139095).