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验证数据展示

  • WB analysis using 67555-1-Ig (same clone as 67555-1-PBS)

    WB analysis using 67555-1-Ig (same clone as 67555-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67555-1-Ig (CRX antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

  • Sample test of MP51402-2

    Sample test of MP51402-2

    Sample test of MP51402-2, CRX Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67555-1-PBS. Detection antibody: 67555-4-PBS.

  • IHC staining of mouse eye using 67555-1-Ig (same clone as 67555-1-PBS)

    IHC staining of mouse eye using 67555-1-Ig (same clone as 67555-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 67555-1-Ig (CRX antibody) at dilution of 1:4000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CRX antibody included
  • Cytometric bead array standard curve of MP51402-2

    Cytometric bead array standard curve of MP51402-2

    Cytometric bead array standard curve of MP51402-2, CRX Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67555-1-PBS. Detection antibody: 67555-4-PBS. Standard:Ag30086. Range: 0.098-100 ng/mL.

CRX Monoclonal antibody, PBS Only (Capture)

CRX Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA, Sample test
Cat No. 67555-1-PBS

产品说明书

CloneNo. 1C3C11

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat, pig

应用

WB, IHC, Cytometric bead array, Indirect ELISA, Sample test

别名

1C3C11, cone rod homeobox, Cone-rod homeobox protein, CORD2, CRD

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy CRX Ready-To-Use IHC Kit. CRX primary antibody included.

产品信息

67555-1-PBS targets CRX as part of a matched antibody pair:

MP51402-2: 67555-1-PBS capture and 67555-4-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, IHC, Cytometric bead array, Indirect ELISA, Sample test Application Description
经测试反应性 human, mouse, rat, pig
免疫原 CRX fusion protein Ag30086 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 cone-rod homeobox
别名 1C3C11, cone rod homeobox, Cone-rod homeobox protein, CORD2, CRD
计算分子量 299 aa, 32 kDa
观测分子量 37 kDa
GenBank蛋白编号BC016664
基因名称 CRX
Gene ID (NCBI) 1406
RRIDAB_2882769
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDO43186
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cone-rod homeobox (Crx) is a homeodomain transcription factor and member of the Otx family, which has been thought to play a critical role in determining and maintaining the phenotype of both pinealocytes and retinal photoreceptors [PMID:17467693]. In the mammalian retina, Crx plays an essential role in the normal development and maintenance of cones and rods and regulates expression of the network of genes that characterize the retina [PMID:17653270]. Elimination of Crx by disruption of the homeobox domain results in loss of the image-forming visual system but not the non-image-forming visual system controlling circadian rhythms [PMID:20438719].