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COQ9 Polyclonal antibody

COQ9 Polyclonal Antibody for WB, IHC, IF/ICC, IP, ELISA
Cat No. 14874-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, IP, ELISA and More (1)

C16orf49, HSPC326, PSEC0129, Ubiquinone biosynthesis protein COQ9, mitochondrial

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells, HEK-293 cells, mouse liver tissue, rat liver tissue
Positive IP detected inHeLa cells
Positive IHC detected inhuman liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inA549 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

14874-1-AP targets COQ9 in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, IP, ELISA Application Description
文献引用应用WB, IF
经测试反应性 human, mouse, rat
文献引用反应性human, rat
免疫原 COQ9 fusion protein Ag6645 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 coenzyme Q9 homolog (S. cerevisiae)
别名 C16orf49, HSPC326, PSEC0129, Ubiquinone biosynthesis protein COQ9, mitochondrial
计算分子量 36 kDa
观测分子量 36 kDa
GenBank蛋白编号BC064946
基因名称 COQ9
Gene ID (NCBI) 57017
RRIDAB_2082218
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO75208
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

COQ9, also named as C16orf49, HSPC326, and PSEC0129, is a 318 amino acid protein, which belongs to the COQ9 family. COQ9 localizes in the Mitochondrion and is involved in the biosynthesis of coenzyme Q COQ9 has abilities to improve left ventricular performance and to reduce myocardial infarct size and cardiomyocyte apoptosis.

实验方案

Product Specific Protocols
WB protocol for COQ9 antibody 14874-1-APDownload protocol
IHC protocol for COQ9 antibody 14874-1-APDownload protocol
IF protocol for COQ9 antibody 14874-1-APDownload protocol
IP protocol for COQ9 antibody 14874-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
ratIF

J Clin Invest

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.

Authors - Heeringa Saskia F SF
humanWB

J Am Soc Nephrol

ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment.

Authors - Eugen Widmeier
humanWB

J Med Genet

Human COQ4 deficiency: delineating the clinical, metabolic and neuroimaging phenotypes.

Authors - Lucia Laugwitz
humanWB

Front Physiol

Human COQ9 Rescues a coq9 Yeast Mutant by Enhancing Coenzyme Q Biosynthesis from 4-Hydroxybenzoic Acid and Stabilizing the CoQ-Synthome.

Authors - Cuiwen H He
humanWB

Mol Genet Metab

Detection of 6-demethoxyubiquinone in CoQ10 deficiency disorders: Insights into enzyme interactions and identification of potential therapeutics.

Authors - Diran Herebian
  • KD Validated
humanIF

J Cell Biol

Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER-mitochondria contacts.

Authors - Kelly Subramanian
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