验证数据展示
产品信息
32695-1-PBS targets COPS7B in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag38543 Product name: Recombinant human COPS7B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 100-264 aa of NM_022730.3 Sequence: TIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVKGLVSSRH* 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) |
| 别名 | COP9 signalosome complex subunit 7b, CSN7B, JAB1-containing signalosome subunit 7b, SGN7b, Signalosome subunit 7b |
| 计算分子量 | 30 kDa，264 aa |
| 观测分子量 | 30 kDa |
| GenBank蛋白编号 | NM_022730.3 |
| 基因名称 | COPS7B |
| Gene ID (NCBI) | 64708 |
| RRID | AB_3742712 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9H9Q2 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
COP9 signalosome complex subunit 7b (COPS7B, also known as CSN7B) is a component of the ribo-interactome that interacts with ribosomes to facilitate ribosome biogenesis and mRNA translation initiation (PMID: 27903243). Increased expression of COPS7B mediated by IGF2BP3 elevates the translational efficiency of genes enriched in mRNA translation and ribosome biogenesis pathways, promoting protein synthesis and driving progression in colorectal cancer (PMID: 37560971).
