验证数据展示
发表文章中的应用
| IHC | See 1 publications below |
产品信息
19670-1-AP targets Collagen Type V in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | IHC |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | collagen, type V, alpha 2 |
| 别名 | COL5A2, Collagen alpha 2(V) chain, Collagen Type V, Collagen V, collagen, type V, alpha 2 |
| 计算分子量 | 145 kDa |
| GenBank蛋白编号 | NM_000393 |
| 基因名称 | COL5A2 |
| Gene ID (NCBI) | 1290 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P05997 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
COL5A2 belongs to the fibrillar collagen family. Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices Defects in COL5A2 are a cause of Ehlers-Danlos syndrome type 1 (EDS1) which also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. This antibody is specific to COL5A2.