验证数据展示
产品信息
10807-1-AP targets COL4A6 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag1118 Product name: Recombinant human COL4A6 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-73 aa of BC005305 Sequence: MLINKLWLLLVTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARHNLQLLNDMAGRLYHFSEVLPNLF 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | collagen, type IV, alpha 6 |
| 别名 | Collagen alpha 6(IV) chain, Collagen alpha-6(IV) chain, Collagen Type IV |
| 计算分子量 | 1691 aa, 164 kDa |
| GenBank蛋白编号 | BC005305 |
| 基因名称 | COL4A6 |
| Gene ID (NCBI) | 1288 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q14031 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Collagen alpha-6(IV) chain, known as COL4A6, is a member of the collagen family, the major structural component of basement membranes. There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. COL4A6 forms a triple helical structure with two other alpha-5-chains, which is stabilized by the presence of glycine as every third residue (PMID: 27377778). COL4A6 is located on the X chromosome in a head-to-head manner with COL4A5 closely (PMID: 23714752). COL4A6 is transcribed from two alternative promoters in a tissue-specific fashion. This antibody detected the cleaved fragment of COL4A6 at ~50 kDa (PMID: 7657706)..
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for COL4A6 antibody 10807-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Oncogene Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA. | ||
Polymers (Basel) The Development of a 3D PET Fibrous Scaffold Modified with an Umbilical Cord dECM for Liver Tissue Engineering | ||
Toxicol Appl Pharmacol High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway. | ||
J Tissue Eng Regen Med Topographical and Chemical Inductive Cues Synergistically Enhance the Schwann Cell Differentiation of Aligned Dental Pulp Stem Cell Sheets | ||
J Immunol Res Partial Reconstruction of Uterus Cervix in Rat by Decellularized Human Uterine Cervical Scaffold Combined with Adipose-Derived Stem Cells (ADSCs) | ||
Oral Dis Artemisinin suppressed tumour growth and induced vascular normalisation in oral squamous cell carcinoma via inhibition of MIF |
