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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis using 22201-1-AP

    WB analysis using 22201-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 22201-1-AP (CNGA4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

CNGA4 Polyclonal antibody

CNGA4 Polyclonal Antibody for WB, ELISA
Cat No. 22201-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

mouse, rat

应用

WB, ELISA

别名

CNCA2, CNG5, CNGA4, CNGB2, OCNC2, OCNCb, OCNCBETA

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inmouse brain tissue, rat brain tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

22201-1-AP targets CNGA4 in WB, ELISA applications and shows reactivity with mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 mouse, rat
免疫原 CNGA4 fusion protein Ag17481 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cyclic nucleotide gated channel alpha 4
别名 CNCA2, CNG5, CNGA4, CNGB2, OCNC2, OCNCb, OCNCBETA
计算分子量 575 aa, 66 kDa
观测分子量47-50 kDa, 65-70 kDa
GenBank蛋白编号BC106936
基因名称 CNGA4
Gene ID (NCBI) 1262
RRIDAB_3669391
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8IV77
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CNGA4 (cyclic nucleotide gated channel subunit alpha 4), also known as CNG4. It is expected to be located in cell membrane. Cyclic nucleotide-gated (CNG) channels are crucial for visual and olfactory transductions (PMID: 12432397). Native CNG channels are heterotetramers composed of homologous A and B subunits. Olfactory CNG channels are composed of three types of subunits, CNGA2, CNGA4, and CNGB1b (PMID: 15134638). CNGA4 is a modulatory subunit which contributes to the high cAMP sensitivity of the native olfactory channel. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation of native olfactory neurons to odorants (PMID: 11739959; 11739960). The molecular weight of CNGA4 is 65 kDa, and it can recognize the 48 kDa isoform.

实验方案

Product Specific Protocols
WB protocol for CNGA4 antibody 22201-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols