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CNDP1 Polyclonal antibody

CNDP1 Polyclonal Antibody for IF/ICC, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF/ICC, IHC, WB, ELISA

Conjugate

Unconjugated

Cat No : 17759-1-AP

Print datasheet

Synonyms

Beta Ala His dipeptidase, Carnosine dipeptidase 1, CN1, CNDP dipeptidase 1, CNDP1, CPGL2, HsT2308, Serum carnosinase

验证数据展示

  • WB analysis of HEK-293 using 17759-1-AP

    WB analysis of HEK-293 using 17759-1-AP

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 17759-1-AP (CNDP1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

  • IHC staining of human prostate cancer using 17759-1-AP

    IHC staining of human prostate cancer using 17759-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 17759-1-AP (CNDP1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human prostate cancer using 17759-1-AP

    IHC staining of human prostate cancer using 17759-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 17759-1-AP (CNDP1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IF Staining of A431 using 17759-1-AP

    IF Staining of A431 using 17759-1-AP

    Immunofluorescent analysis of A431 cells using 17759-1-AP (CNDP1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

经过测试的应用

Positive WB detected inHEK-293 cells, A431 cells
Positive IHC detected inhuman prostate cancer tissue, mouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inA431 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IHCSee 1 publications below

产品信息

17759-1-AP targets CNDP1 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IF/ICC, IHC, WB, ELISA
Cited ApplicationsIHC
Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Immunogen CNDP1 fusion protein Ag12127 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name carnosine dipeptidase 1 (metallopeptidase M20 family)
Synonyms Beta Ala His dipeptidase, Carnosine dipeptidase 1, CN1, CNDP dipeptidase 1, CNDP1, CPGL2, HsT2308, Serum carnosinase
Calculated Molecular Weight 508 aa, 57 kDa
Observed Molecular Weight 57 kDa
GenBank Accession NumberBC110295
Gene Symbol CNDP1
Gene ID (NCBI) 84735
RRIDAB_2878435
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96KN2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Beta-Ala-His dipeptidase (CNDP1) encodes the secreted serum carnosinase, which is synthesized in the brain and secreted into the systematic circulation, CNDP1 hydrolyzes L-carnosine and is essential for glucose metabolism and the transportation of activated fatty acids across the mitochondrial membrane (PMID: 32111749, 16046297).

实验方案

Product Specific Protocols
WB protocol for CNDP1 antibody 17759-1-APDownload protocol
IHC protocol for CNDP1 antibody 17759-1-APDownload protocol
IF protocol for CNDP1 antibody 17759-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Amino Acids

Serum and urinary carnosinase-1 correlate with kidney function and inflammation

Authors - Shiqi Zhang
View Article