验证数据展示
经过测试的应用
| Positive WB detected in | mouse testis tissue, rat testis tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
34038-1-AP targets CMTM1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag40585 Product name: Recombinant human CMTM1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 237-286 aa of BC057852 Sequence: VIVCCIDAFVVTTKMRTNLKRFLGVEVERKLSPAKDAYPETGPDAPQRPA 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | CKLF-like MARVEL transmembrane domain containing 1 |
| 别名 | 2, Chemokine-like factor superfamily member 1, CKLF-like MARVEL transmembrane domain-containing protein 1, CKLFSF1 |
| 计算分子量 | 19 kDa |
| 观测分子量 | 29 kDa |
| GenBank蛋白编号 | BC057852 |
| 基因名称 | CMTM1 |
| Gene ID (NCBI) | 113540 |
| RRID | AB_3743141 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q8IZ96 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CMTM1 is a MARVEL domain-containing membrane protein enriched in testis and epithelial tissues, with emerging roles in membrane trafficking and cell survival. Its frequent overexpression in multiple cancers and association with aggressive tumor behavior suggest that CMTM1 contributes to tumor progression, potentially by modulating membrane organization or receptor signaling. These properties position CMTM1 as a candidate biomarker and functional regulator in cancer biology (PMID: 33585698, 31542285).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for CMTM1 antibody 34038-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
