验证数据展示
经过测试的应用
Positive WB detected in | ARPE-19 cells |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
27498-1-AP targets CLUL1 in WB, ELISA applications and shows reactivity with human samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | human |
免疫原 | CLUL1 fusion protein Ag26570 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | clusterin-like 1 (retinal) |
别名 | Retinal-specific clusterin-like protein, Clusterin-like protein 1, Clusterin like protein 1, clusterin like 1 (retinal) |
计算分子量 | 54 kDa |
观测分子量 | 70 kDa |
GenBank蛋白编号 | BC025381 |
基因名称 | CLUL1 |
Gene ID (NCBI) | 27098 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q15846 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Clusterin-like protein 1 (CLUL1) functions as a molecular chaperone, protecting stressed proteins, and is upregulated in various neurodegenerative conditions, suggesting a role in defense against neuronal damage (PMID: 17148042). It is specifically expressed in cone photoreceptor cells and is regulated by the cone-rod homeobox (CRX) (PMID: 14507903). Mutations of CLUL1 were investigated in the context of age-related macular degeneration (AMD), a leading cause of blindness in the elderly (PMID: 17148042).
实验方案
Product Specific Protocols | |
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WB protocol for CLUL1 antibody 27498-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |