验证数据展示
经过测试的应用
| Positive WB detected in | A549 cells, HeLa cells, Jurkat cells, K-562 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
31683-1-AP targets CIZ1 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | CIZ1 fusion protein Ag35418 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | CDKN1A interacting zinc finger protein 1 |
| 别名 | ZNF356, NP94, LSFR1, CIZ 1, Cip1-interacting zinc finger protein |
| 观测分子量 | 140 kDa |
| GenBank蛋白编号 | BC021163 |
| 基因名称 | CIZ1 |
| Gene ID (NCBI) | 25792 |
| RRID | AB_3670077 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9ULV3 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CIZ1, also known as LSFR1 and ZNF356, is a nuclear protein and the binding partner of p21. The full-length CIZ1 consists of 842 amino acid (aa) residues and contains two glutamine-rich domains, three C2H2-type zinc finger motifs, one acidic domain, and one MH3 domain (PMID: 10529385). Dysregulated or point mutated CIZ1 has been implicated in neurodegenerative, autoimmune and cancer diseases.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for CIZ1 antibody 31683-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |