• Featured Product
  • KD/KO验证

CGGBP1 Polyclonal antibody

CGGBP1 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 10716-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA and More (4)

20 kDa CGG binding protein, CGG binding protein 1, CGGBP, CGGBP1, p20 CGGBP, p20 CGGBP DNA binding protein

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells, mouse thymus tissue, K-562 cells, Raji cells, HL-60 cells, Jurkat cells, rat thymus tissue
Positive IHC detected inhuman breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy CGGBP1 Ready-To-Use IHC Kit. CGGBP1 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10716-1-AP targets CGGBP1 in WB, IHC, IF, IP, chIP, Dot Blot, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IF, IP, chIP, Dot Blot
经测试反应性 human, mouse, rat
文献引用反应性human
免疫原 CGGBP1 fusion protein Ag1129 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 CGG triplet repeat binding protein 1
别名 20 kDa CGG binding protein, CGG binding protein 1, CGGBP, CGGBP1, p20 CGGBP, p20 CGGBP DNA binding protein
计算分子量 19 kDa
观测分子量 19-23 kDa
GenBank蛋白编号BC005222
基因名称 CGGBP1
Gene ID (NCBI) 8545
RRIDAB_2079283
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UFW8
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CGGBP1, also named as CGGBP, is a 20 kDa CGG-binding protein. It binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. CGGBP1 may play a role in regulating FMR1 promoter. It is a bona fide midbody protein required for normal abscission and mitosis in general.(PMID:20832400)

实验方案

Product Specific Protocols
WB protocol for CGGBP1 antibody 10716-1-APDownload protocol
IHC protocol for CGGBP1 antibody 10716-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIP

Cell Cycle

CGGBP1 phosphorylation constitutes a telomere-protection signal.

Authors - Umashankar Singh
  • KD Validated
humanchIP

Cell Cycle

Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs.

Authors - Prasoon Agarwal
humanWB,IP

Epigenetics Chromatin

CGGBP1 regulates CTCF occupancy at repeats.

Authors - Divyesh Patel
humanIF

Exp Cell Res

CGGBP1 is a nuclear and midbody protein regulating abscission.

Authors - Singh Umashankar U
humanWB,Dot Blot

BMC Cancer

An immunochemistry-based screen for chemical inhibitors of DNA-protein interactions and its application to human CGGBP1.

Authors - Manthan Patel
humanWB

BMC Genet

CGGBP1-regulated cytosine methylation at CTCF-binding motifs resists stochasticity.

Authors - Manthan Patel
Loading...