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验证数据展示

  • IHC staining of human brain using 21815-1-AP (same clone as 21815-1-PBS)

    IHC staining of human brain using 21815-1-AP (same clone as 21815-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 21815-1-AP (CEP152 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21815-1-PBS in a different storage buffer formulation.

  • WB analysis using 21815-1-AP (same clone as 21815-1-PBS)

    WB analysis using 21815-1-AP (same clone as 21815-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21815-1-AP (CEP152 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21815-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 21815-1-AP (same clone as 21815-1-PBS)

    IP experiment of mouse brain using 21815-1-AP (same clone as 21815-1-PBS)

    IP result of anti-CEP152 (IP:21815-1-AP, 4ug; Detection:21815-1-AP 1:2000) with mouse brain tissue lysate 1280 ug. This data was developed using the same antibody clone with 21815-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 21815-1-AP (same clone as 21815-1-PBS)

    IHC staining of human brain using 21815-1-AP (same clone as 21815-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 21815-1-AP (CEP152 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21815-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse brain using 21815-1-AP (same clone as 21815-1-PBS)

    WB analysis of mouse brain using 21815-1-AP (same clone as 21815-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 21815-1-AP (CEP152 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21815-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

CEP152 Polyclonal antibody, PBS Only

CEP152 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 21815-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

KIAA0912, centrosomal protein 152kDa, CEP 152

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

21815-1-PBS targets CEP152 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 centrosomal protein 152kDa
别名 KIAA0912, centrosomal protein 152kDa, CEP 152
计算分子量 189 kDa
观测分子量 66 kDa
GenBank蛋白编号NM_014985
基因名称 CEP152
Gene ID (NCBI) 22995
RRIDAB_2878921
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO94986
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CEP152, also named as KIAA0912, is a regulator of genomic integrity and cellular response to DNA damage acting through ATR-mediated checkpoint signaling. It is necessary for centrosome duplication. CEP152 functions as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, two molecules involved in centriole formation. CEP152, ATR and CENPJ control cellular responses to DNA damage. CEP152 has some isoforms with MW 189 kDa, 152 kDa, 110 kDa and 66 kDa.

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