验证数据展示
产品信息
28835-1-PBS targets CELSR3 in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | IHC, IF-P, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag28746 Product name: Recombinant human CELSR3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 2285-2540 aa of NM_001407 Sequence: MPGGSPGSAGLVRHLEEYAATLARNMELTYLNPMGLVTPNIMLSIDRMEHPSSPRGARRYPRYHSNLFRGQDAWDPHTHVLLPSQSPRPSPSEVLPTSSSIENSTTSSVVPPPAPPEPEPGISIIILLVYRTLGGLLPAQFQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRGILESPISLEFRLLQTANRSKAICVQWDPPGLAEQHGVWTARDCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLA 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) |
| 别名 | |
| 计算分子量 | 358 kDa |
| GenBank蛋白编号 | NM_001407 |
| 基因名称 | CELSR3 |
| Gene ID (NCBI) | 1951 |
| RRID | AB_3086089 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9NYQ7 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Atypical cadherin Celsr3 plays critical roles during brain development, in collaboration with Fzd3. Celsr3 is required for postnatal cerebellar Purkinje cell maturation and synaptic plasticity, which has potential implications in neural disorders implicating the cerebellum.

