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验证数据展示

  • WB analysis using 85384-2-RR

    WB analysis using 85384-2-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 85384-2-RR (CDSN antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

  • IHC staining of human skin cancer using 85384-2-RR

    IHC staining of human skin cancer using 85384-2-RR

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 85384-2-RR (CDSN antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human skin cancer using 85384-2-RR

    IHC staining of human skin cancer using 85384-2-RR

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 85384-2-RR (CDSN antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CDSN Recombinant monoclonal antibody

CDSN Uni-rAb® Recombinant Antibody for WB, IHC, ELISA
Cat No. 85384-2-RR

产品说明书

CloneNo. 261055C11

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA

别名

corneodesmosin, D6S586E, HTSS, S protein

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inmouse skin tissue, rat skin tissue
Positive IHC detected inhuman skin cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:10000
Immunohistochemistry (IHC)IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

85384-2-RR targets CDSN in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Eg10164

Product name: Recombinant Human CDSN protein (rFc Tag)

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 33-529 aa of NM_001264.5

Sequence: KSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGNSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGKIPCRSIRDILAQVKPLGPQLADPEVFLPQGELLNSP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 corneodesmosin
别名 corneodesmosin, D6S586E, HTSS, S protein
计算分子量52 kDa
观测分子量55-65 kDa
GenBank蛋白编号NM_001264.5
基因名称 CDSN
Gene ID (NCBI) 1041
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ15517
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CDSN, also named as S protein, is important for the epidermal barrier integrity. CDSN is a unique extracellular 52- to 56-kDa glycoprotein found in corneodesmosomes. Pathogenic mutations in CDSN have been linked in humans to genodermatoses affecting both the hair follicle and the epidermis. Inflammatory peeling skin syndrome is caused a novel mutation in CDSN.

实验方案

Product Specific Protocols
IHC protocol for CDSN antibody 85384-2-RRDownload protocol
WB protocol for CDSN antibody 85384-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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