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Cadherin-11 Polyclonal antibody

Cadherin-11 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 12028-1-AP

Print datasheet

Synonyms

CAD11, Cadherin 11, Cadherin-11, CDH11, CDHOB, OB, OB cadherin, OSF 4, Osteoblast cadherin

验证数据展示

  • WB analysis of PC-3 using 12028-1-AP

    WB analysis of PC-3 using 12028-1-AP

    PC-3 cells were subjected to SDS PAGE followed by western blot with 12028-1-AP (Cadherin-11 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inPC-3 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

12028-1-AP targets Cadherin-11 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA
Tested Reactivity human
Immunogen Cadherin-11 fusion protein Ag2659 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name cadherin 11, type 2, OB-cadherin (osteoblast)
Synonyms CAD11, Cadherin 11, Cadherin-11, CDH11, CDHOB, OB, OB cadherin, OSF 4, Osteoblast cadherin
Calculated Molecular Weight 796 aa, 88 kDa
Observed Molecular Weight120 kDa
GenBank Accession NumberBC013609
Gene Symbol CDH11
Gene ID (NCBI) 1009
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP55287
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. Cadherin-11 (CDH11), also known osteoblast cadherin (OB-cadherin) or OSF-4, was identified initially in a mouse osteoblastic cell line and human osteosarcoma (PMID: 8163513). Cadherin-11 is a single pass transmembrane protein consisting of an extracellular domain which contains five repeat sequences (EC1-EC5), a transmembrane segment and a cytoplasmic domain which links catenins to the actin and microtubule cytoskeleton (PMID: 8163513; 33442417). It has been shown that cadherin-11 plays important roles in the occurrence and development of a lot of diseases, arthritis, cancer, aortic calcification disease, dermatosis (PMID: 33442417).

实验方案

Product Specific Protocols
WB protocol for Cadherin-11 antibody 12028-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols