验证数据展示
经过测试的应用
| Positive FC detected in | human peripheral blood lymphocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65071-1-Ig targets CD95 in FC applications and shows reactivity with Human samples.
| 经测试应用 | FC Application Description |
| 经测试反应性 | Human |
| 免疫原 | Human CD95 transfected L cells 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | Fas (TNF receptor superfamily, member 6) |
| 别名 | ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6 |
| 计算分子量 | 35-38 kDa |
| GenBank蛋白编号 | BC012479 |
| 基因名称 | Fas/CD95 |
| Gene ID (NCBI) | 355 |
| RRID | AB_2918377 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P25445 |
| 储存缓冲液 | Borate buffered saline , pH 8.2 |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CD95 antibody 65071-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |