验证数据展示
经过测试的应用
| Positive FC detected in | human peripheral blood platelets |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65070-1-Ig targets CD9 in FC applications and shows reactivity with human samples.
| 经测试应用 | FC Application Description |
| 经测试反应性 | human |
| 免疫原 | N/A 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | CD9 molecule |
| 别名 | CD9 molecule, CD9 antigen, BTCC 1, BA2, 5H9 antigen |
| 计算分子量 | 228 aa, 25 kDa |
| GenBank蛋白编号 | BC011988 |
| 基因名称 | CD9 |
| Gene ID (NCBI) | 928 |
| RRID | AB_2918376 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P21926 |
| 储存缓冲液 | Borate buffered saline , pH 8.2 |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD9, also known as Tspan-29, p24 or MIC3, is a member of the tetraspanin superfamily (PMID: 1879540). It is expressed on a large variety of hematopoietic and non-hematopoietic cells, such as stromal cells, megakaryocytes, platelets, B and T lymphocytes, dendritic cells, endothelial cells, mast cells, eosinophils, and basophils (PMID: 30356731). CD9 interacts with the integrin family and other membrane proteins, and is involved in cell adhesion, cell motility and tumor metastasis (PMID: 8478605; 21428940; 25805926). Expression of CD9 enhances membrane fusion between muscle cells and support myotube maintenance (PMID:10459022). On oocytes, CD9 is hypothesized to play a role in fertilization of mammals (PMID: 25536312).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CD9 antibody 65070-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |