• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of Daudi using 67424-1-Ig (same clone as 67424-1-PBS)

    WB analysis of Daudi using 67424-1-Ig (same clone as 67424-1-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 67424-1-Ig (CD72 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67424-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67424-1-Ig (same clone as 67424-1-PBS)

    IHC staining of human tonsillitis using 67424-1-Ig (same clone as 67424-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67424-1-Ig (CD72 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67424-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67424-1-Ig (same clone as 67424-1-PBS)

    IHC staining of human tonsillitis using 67424-1-Ig (same clone as 67424-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67424-1-Ig (CD72 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67424-1-PBS in a different storage buffer formulation.

  • IF Staining of Ramos using 67424-1-Ig (same clone as 67424-1-PBS)

    IF Staining of Ramos using 67424-1-Ig (same clone as 67424-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Ramos cells using CD72 antibody (67424-1-Ig, Clone: 2C1C6 ) at dilution of 1:1600 and CoraLite®594-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67424-1-PBS in a different storage buffer formulation.

  • IF Staining of human tonsillitis using 67424-1-Ig (same clone as 67424-1-PBS)

    IF Staining of human tonsillitis using 67424-1-Ig (same clone as 67424-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CD72 antibody (67424-1-Ig, Clone: 2C1C6 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67424-1-PBS in a different storage buffer formulation.

CD72 Monoclonal antibody, PBS Only

CD72 Monoclonal Antibody for WB, IHC, IF/ICC, IF-P, Indirect ELISA
Cat No. 67424-1-PBS

产品说明书

CloneNo. 2C1C6

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

WB, IHC, IF/ICC, IF-P, Indirect ELISA

别名

2C1C6, B-cell differentiation antigen CD72, CD72 molecule, CD72b, Lyb 2

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

67424-1-PBS targets CD72 in WB, IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, IF-P, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag14405

Product name: Recombinant human CD72 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 116-359 aa of BC030227

Sequence: VRYLQVSQQLQQTNRVLEVTNSSLRQQLRLKITQLGQSAEDLQGSRRELAQSQEALQVEQRAHQAAEGQLQACQADRQKTKETLQSEEQQRRALEQKLSNMENRLKPFFTCGSADTCCPSGWIMHQKSCFYISLTSKNWQESQKQCETLSSKLATFSEIYPQSHSYYFLNSLLPNGGSGNSYWTGLSSNKDWKLTDDTQRTRTYAQSSKCNKVHKTWSWWTLESESCRSSLPYICEMTAFRFPD

种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 CD72 molecule
别名 2C1C6, B-cell differentiation antigen CD72, CD72 molecule, CD72b, Lyb 2
计算分子量 359 aa, 40 kDa
观测分子量40 kDa
GenBank蛋白编号BC030227
基因名称 CD72
Gene ID (NCBI) 971
RRIDAB_2882663
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP21854
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD72 is a type II transmembrane glycoprotein of 39-45 kDa and is expressed as a disulphide-linked homodimer (PMID: 1711157). CD72 is a pan B-cell marker covering the full range of differentiation from the very early stages of B cells to mature surface Ig+ B cells (PMID: 1384316). It is expressed in all stages of B cell development except plasma cells. CD72 is also expressed by dendritic cells, tissue macrophages in the red pulp of the spleen and von Kupffer cells in the liver (PMID: 8561576; 1384316). CD72 is the ligand for CD5 (PMID: 1711157). CD72 is a negative regulator of BCR signaling (PMID: 9590210). Interaction of CD100 with CD72 strictly tunes the strength of BCR signals and is essential for maintaining immunological homeostasis as well as generating a proper immune response (PMID: 16113236).

||
New chat Able
正在加载，请稍候...