验证数据展示
产品信息
84766-3-PBS targets CD71 in IF/ICC, Indirect ELISA applications and shows reactivity with mouse samples.
经测试应用 | IF/ICC, Indirect ELISA Application Description |
经测试反应性 | mouse |
免疫原 | Recombinant protein 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | transferrin receptor |
别名 | Tfrc, transferrin receptor, TR, TFR1, TFR |
计算分子量 | 86kDa |
GenBank蛋白编号 | NM_011638.4 |
基因名称 | CD71 |
Gene ID (NCBI) | 22042 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q62351 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.