Anti-Mouse CD62L (MEL14)

CD62L Monoclonal Antibody for FC
Cat No. 65219-1-Ig

产品说明书

CloneNo. MEL14

宿主/亚型

Rat / IgG2a, kappa

种属反应性

Mouse

应用

FC

AI528707, CD62L, L selectin, LECAM 1, Lnhr, Ly 22, Ly m22, Lyam 1, Lyam1, selectin, lymphocyte, Sell

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inmouse splenocytes

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

65219-1-Ig targets CD62L in FC applications and shows reactivity with Mouse samples.

经测试应用 FC Application Description
经测试反应性 Mouse
免疫原 C3H/eb mouse B lymphoma 38C-13 种属同源性预测
宿主/亚型 Rat / IgG2a, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 selectin, lymphocyte
别名 AI528707, CD62L, L selectin, LECAM 1, Lnhr, Ly 22, Ly m22, Lyam 1, Lyam1, selectin, lymphocyte, Sell
GenBank蛋白编号BC052681
基因名称 CD62L
Gene ID (NCBI) 20343
RRIDAB_3084906
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP18337
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Stable for one year after shipment.

背景介绍

CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes (PMID: 1382078; 1694883, 1695155). CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078).

实验方案

Product Specific Protocols
FC protocol for CD62L antibody 65219-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...