Anti-Human CD54 (ICAM-1) (15.2), PBS Only
CD54 (ICAM-1) Monoclonal Antibody for Sandwich ELISA, Indirect ELISA
Host / Isotype
Mouse / IgG1, kappa
Reactivity
Human
Applications
Sandwich ELISA, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
15.2
验证数据展示
产品信息
65075-1-PBS targets CD54 (ICAM-1) as part of a matched antibody pair:
MP50085-1: 65075-1-PBS capture and 68693-1-PBS detection (validated in Sandwich ELISA)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Applications | Sandwich ELISA, Indirect ELISA |
| Tested Reactivity | Human |
| Immunogen | Rheumatoid synovial cells and human monocytes 种属同源性预测 |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | intercellular adhesion molecule 1 |
| Synonyms | BB2, CD54, ICAM 1, ICAM1, ICAM-1, P3.58 |
| Calculated Molecular Weight | 90 kDa |
| GenBank Accession Number | BC015969 |
| Gene Symbol | ICAM1 |
| Gene ID (NCBI) | 3383 |
| ENSEMBL Gene ID | ENSG00000090339 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Affinity purification |
| UNIPROT ID | P05362 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
背景介绍
ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).