验证数据展示
产品信息
83451-1-PBS targets CD5 as part of a matched antibody pair:
MP00448-1: 83451-1-PBS capture and 83451-3-PBS detection (validated in Cytometric bead array)
MP00448-2: 83451-1-PBS capture and 83451-2-PBS detection (validated in Cytometric bead array, Sandwich ELISA)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| 经测试应用 | Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test Application Description |
| 经测试反应性 | mouse |
| 免疫原 | CD5 fusion protein Eg0899 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | CD5 antigen |
| 别名 | CD5 antigen, Ly 1, Ly 12, Ly A, Lyt 1 |
| 计算分子量 | 54 kDa |
| GenBank蛋白编号 | NM_007650.3 |
| 基因名称 | Cd5 |
| Gene ID (NCBI) | 12507 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P13379 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family (PMID: 12403363). CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells (PMID: 9858516; 6156984; 10379049; 1384337). CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development (PMID: 7542801).