验证数据展示
产品信息
55118-1-PBS targets CD336 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | natural cytotoxicity triggering receptor 2 |
| 别名 | NCR2, LY95, Lymphocyte antigen 95 homolog, Natural killer cell p44-related protein, NK cell activating receptor |
| 计算分子量 | 31 kDa |
| 观测分子量 | 36-44 kDa |
| GenBank蛋白编号 | NM_004828 |
| 基因名称 | CD336 |
| Gene ID (NCBI) | 9436 |
| RRID | AB_10888637 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O95944 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD336, also named as NCR2, LY95 and NKp44, belongs to the natural cytotoxicity receptor (NCR) family. It is cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. It is expressed on activated human NK cells. CD336 displays a single extracellular Ig-like V domain and a transmembrane portion containing the charged residue (Lysine), likely involved in the association with KARAP/DAP12 molecules. The antibody is specific to CD336.
