Mouse CD31 Recombinant antibody, PBS Only

CD31 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 84607-4-PBS

产品说明书

CloneNo. 242041E12

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, IF/ICC, Indirect ELISA

Pecam1, PECAM 1, Pecam, 242041E12

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

84607-4-PBS targets CD31 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with mouse samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 platelet/endothelial cell adhesion molecule 1
别名 Pecam1, PECAM 1, Pecam, 242041E12
计算分子量81 kDa
观测分子量100-130 kDa
GenBank蛋白编号NM_001305157.1
基因名称 CD31
Gene ID (NCBI) 18613
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ08481-1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

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