验证数据展示
产品信息
87577-1-PBS targets CD296/ART1 in WB, Indirect ELISA applications and shows reactivity with mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | mouse, rat |
| 免疫原 |
CatNo: Eg6314 Product name: Recombinant mouse CD296/ART1 protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 23-290 aa of NM_009710.4 Sequence: QSYSISQLDIFSQETPLDMAPASFDDQYAGCLADMTAALPDLNHSEFQANKVYADGWAQANNQWQERRAWGSVWGSLPPSPPGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLRSHRSRGCQQVYRGVHGLRFRPAGPGATVRLGGFASASLKNVAAQQFGEDTFFGIWTCLGAPIRGYSFFPEEEEVLIPPFETFQVINTSRPTQGPARIYLRALGKRSTYNCEYIKEKKCRSGPCWLGSS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | ADP-ribosyltransferase 1 |
| 别名 | |
| 计算分子量 | 36 kDa |
| 观测分子量 | 40 kDa |
| GenBank蛋白编号 | NM_009710.4 |
| 基因名称 | Art1 |
| Gene ID (NCBI) | 11870 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q60935 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD296 (ART1) is a GPI-anchored ecto-ADP-ribosyltransferase that catalyzes extracellular mono-ADP-ribosylation of cell-surface proteins. By modifying integrins and other membrane-associated targets, ART1 regulates cell adhesion, migration, and inflammatory signaling. Its overexpression in multiple cancers and involvement in airway and tissue remodeling highlight ART1 as a functional mediator at the interface of cell-surface modification and disease progression.
