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验证数据展示

  • FC experiment of mouse splenocytes using 98160-1-RR (same clone as 98160-1-PBS)

    FC experiment of mouse splenocytes using 98160-1-RR (same clone as 98160-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD27 Rabbit Recombinant Antibody (98160-1-RR, Clone:241378E11) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). cells were co-stained with APC Anti-mouse CD3. Cells were not fixed. This data was developed using the same antibody clone with 98160-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse splenocytes using 98160-1-RR (same clone as 98160-1-PBS)

    FC experiment of mouse splenocytes using 98160-1-RR (same clone as 98160-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD27 Rabbit Recombinant Antibody (98160-1-RR, Clone: 241378E11) (red), or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98160-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98160-1-RR

    Affinity and Kinetic Characterization of 98160-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98160-1-RR against Mouse CD27 were performed. The affinity constant is 1.87 nM.

Anti-Mouse CD27 Rabbit Recombinant Antibody, PBS Only

CD27 Uni-rAb® Recombinant Antibody for FC
Cat No. 98160-1-PBS

产品说明书

CloneNo. 241378E11

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

241378E11, CD27 antigen, CD27L receptor, T-cell activation antigen CD27, TNFRSF7

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98160-1-PBS targets CD27 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原

CatNo: Eg1311

Product name: Recombinant Mouse CD27 protein (His Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-6*HIS

Domain: 21-182 aa of NM_001033126.2

Sequence: TLAPNSCPDKHYWTGGGLCCRMCEPGTFFVKDCEQDRTAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECSCSKNWQCRDQECTECDPPLNPALTRQPSETPSPQPPPTHLPHGTEKPSWPLHRQLPNSTVYSQRSSHRPLCSSDCIR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD27 antigen
别名 241378E11, CD27 antigen, CD27L receptor, T-cell activation antigen CD27, TNFRSF7
计算分子量28kDa
GenBank蛋白编号NM_001033126.2
基因名称 CD27
Gene ID (NCBI) 21940
RRIDAB_3672303
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP41272
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (CD27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1.

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