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验证数据展示

  • WB analysis of mouse brain using 87759-3-RR (same clone as 87759-3-PBS)

    WB analysis of mouse brain using 87759-3-RR (same clone as 87759-3-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 87759-3-RR (CD232/PLXNC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87759-3-PBS in a different storage buffer formulation.

  • IHC staining of mouse spleen using 87759-3-RR (same clone as 87759-3-PBS)

    IHC staining of mouse spleen using 87759-3-RR (same clone as 87759-3-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 87759-3-RR (CD232/PLXNC1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87759-3-PBS in a different storage buffer formulation.

  • Affinity of 87759-3-RR

    Affinity of 87759-3-RR

    Biolayer interferometry (BLI) kinetic assays of 87759-3-RR against Mouse CD232/PLXNC1 were performed. The affinity constant is below 1 pM.

Mouse CD232/PLXNC1 Recombinant monoclonal antibody, PBS Only

CD232/PLXNC1 Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 87759-3-PBS

产品说明书

CloneNo. 252223A10

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, IHC, Indirect ELISA

别名

CD232, Plexin-C1, Plxnc1, Vespr

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

87759-3-PBS targets CD232/PLXNC1 in WB, IHC, Indirect ELISA applications and shows reactivity with mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 mouse
免疫原

CatNo: Eg6304

Product name: Recombinant mouse CD232/PLXNC1 protein

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 35-950 aa of NM_018797.3

Sequence: ADEPVWRSEQAIGAIAASRADGVFVASGSCLDQLDYSLKNRLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGATGLEGLLLTGWTFDRGACEVRPLGNLNRSSLRNGTEVVSCHPQGSTAGVVYRASGTDLWYLAVAATYVLPEPETANRCNPAASDRDTAIALKNTEGRSLATQELGRLKLRGSAGSLHFVDAFLWNGSVYFPYYPYNYTSGAATGWPSMARIAQSTEVLFQGQAALDCDHGHPEGRRLLLSSSLVEAVDIWAGVFSAATGEGQERRSPATTALCLFRMSEIQAHARSCSWDFQATEHNCKEGDRPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVVLGENLTSNCPEVIYEIKEETPVFYKLVPHPMKNIYIYLTAGKEVRRIPVANCSKRKSCSECLAAADPHCGWCLPLQRCTFQGDCTHAGSFENWLDISSGPKKCPKIQILRSLRERTTVTIVGSISARHSECVVKNADTGKLLCQGRSQLNWTCACNIPSRPSYNVLVVNATFSFPSWNLSERFNFTNCASLKECPACIRSGCAWCKRDKKCIHPFTPCEPSDYERNQELCQVAVEKSPKDSGGGRVKESKRNRTDGAVQVFYIKAIEPQKISTLGKSNVIVTGANFTQASNITMILRGTSTCERDVIRVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGTCSSAGALSYIALPHCSLIVPATTWISGGQNITIMGRNFDVIDNLIISHELKGNANVNINVSEYCAATFCRFLAPNLKSSKVRTNVAVKLRVQDTYLDCGTLQYLEDPRFTGYRVESEIDTELEVKIQKENDNFNISKDDIDITLFHGENKQFNCSFENITRNQDLTTILCKIKSIKNANTIASSSKKVRVKLGNLELYVEQESVPST

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 plexin C1
别名 CD232, Plexin-C1, Plxnc1, Vespr
计算分子量176 kDa
观测分子量220 kDa
GenBank蛋白编号NM_018797.3
基因名称 Plxnc1
Gene ID (NCBI) 54712
RRIDAB_3745738
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9QZC2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD232/PLXNC1 is a class C plexin surface receptor that mediates SEMA7A-dependent signaling to control cell migration, adhesion, and cytoskeletal dynamics in immune and stromal compartments. Its expression in monocytes/macrophages, dendritic cells, and endothelial-associated tissues supports important roles in inflammation, tissue remodeling, and fibrotic responses. Dysregulation of the PLXNC1 signaling axis has been linked to tumor progression, vascular inflammation, and fibrosis, highlighting PLXNC1 as a multifunctional receptor in immune and microenvironmental biology.

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