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验证数据展示

  • FC experiment of human PBMCs using 98002-2-RR (same clone as 98002-2-PBS)

    FC experiment of human PBMCs using 98002-2-RR (same clone as 98002-2-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD226 Rabbit Recombinant Antibody (98002-2-RR, Clone: 240673G4) or Isotype Control, and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3 . Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98002-2-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98002-2-RR (same clone as 98002-2-PBS)

    FC experiment of human PBMCs using 98002-2-RR (same clone as 98002-2-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD226 Rabbit Recombinant Antibody (98002-2-RR, Clone:240673G4) (red) or Isotype Control (blue) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98002-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98002-2-RR

    Affinity and Kinetic Characterization of 98002-2-RR

    Biolayer interferometry (BLl) kinetic assays of 98036-1-RR against Human CD226 were performed. The affinity constant is 3.70 nM.

Anti-Human CD226 Rabbit Recombinant Antibody, PBS Only

CD226 Uni-rAb® Recombinant Antibody for FC
Cat No. 98002-2-PBS

产品说明书

CloneNo. 240673G4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

240673G4, CD226 antigen, CD226 molecule, DNAM 1, DNAM1

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98002-2-PBS targets CD226 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg0027

Product name: Recombinant Human CD226 protein (Myc Tag, His Tag)

Source: mammalian cells-derived, pHZ-KIsec

Tag: Myc & 6*His

Domain: 19-247 aa of BC074787

Sequence: EEVLWHTSVPFAENMSLECVYPSMGILTQVEWFKIGTQQDSIAIFSPTHGMVIRKPYAERVYFLNSTMASNNMTLFFRNASEDDVGYYSCSLYTYPQGTWQKVIQVVQSDSFEAAVPSNSHIVSEPGKNVTLTCQPQMTWPVQAVRWEKIQPRQIDLLTYCNLVHGRNFTSKFPRQIVSNCSHGRWSVIVIPDVTVSDSGLYRCYLQASAGENETFVMRLTVAEGKTDN

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD226 molecule
别名 240673G4, CD226 antigen, CD226 molecule, DNAM 1, DNAM1
计算分子量 336 aa, 39 kDa
GenBank蛋白编号BC074787
基因名称 CD226
Gene ID (NCBI) 10666
ENSEMBL Gene IDENSG00000150637
RRIDAB_3672146
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ15762
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).

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