验证数据展示
产品信息
84095-6-PBS targets CD209 in WB, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | Fusion Protein 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | CD209 molecule |
别名 | DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN |
计算分子量 | 404 aa, 45.7 kDa |
观测分子量 | 48 kDa |
GenBank蛋白编号 | BC110615 |
基因名称 | CD209 |
Gene ID (NCBI) | 30835 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q9NNX6 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).