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验证数据展示

  • WB analysis of human skin using 11841-1-AP

    WB analysis of human skin using 11841-1-AP

    human skin tissue were subjected to SDS PAGE followed by western blot with 11841-1-AP (Langerin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  • IHC staining of human skin cancer using 11841-1-AP

    IHC staining of human skin cancer using 11841-1-AP

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 11841-1-AP (Langerin antibody) at dilution of 1:6000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human skin cancer using 11841-1-AP

    IHC staining of human skin cancer using 11841-1-AP

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 11841-1-AP (Langerin antibody) at dilution of 1:6000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CD207 Polyclonal antibody

CD207 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 11841-1-AP

产品说明书

引用文献(1)

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, ELISA

别名

Langerin, CD207 molecule, langerin, CLEC4K, C-type lectin domain family 4 member K

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inhuman skin tissue, mouse skin tissue
Positive IHC detected inhuman skin cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:3000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11841-1-AP targets CD207 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, mouse
免疫原 CD207 fusion protein Ag2479 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 CD207 molecule, langerin
别名 Langerin, CD207 molecule, langerin, CLEC4K, C-type lectin domain family 4 member K
计算分子量 328 aa, 37 kDa
观测分子量 40 kDa
GenBank蛋白编号BC022278
基因名称 CD207
Gene ID (NCBI) 50489
RRIDAB_2074314
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UJ71
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CD207 protein (also known as langerin protein) is encoded by the CD207 gene and is a type of C-type lectin receptor that is specifically expressed on the surface of LCs. It is one of the specific immunohistochemical markers of LCs (PMID: 37383183, PMID: 28109175). CD207 plays an important role in a series of non-classical antigen processing processes, such as forming Birbeck granules and processing and transporting them to local lymphoid tissue, and inducing LC maturation (PMID: 32326440).

实验方案

Product Specific Protocols
WB protocol for CD207 antibody 11841-1-APDownload protocol
IHC protocol for CD207 antibody 11841-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle

Elife

Cryo-electron tomography of Birbeck granules reveals the molecular mechanism of langerin lattice formation.

Authors - Toshiyuki Oda
View Article