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验证数据展示

  • WB analysis of fetal human brain using 66282-1-Ig (same clone as 66282-1-PBS)

    WB analysis of fetal human brain using 66282-1-Ig (same clone as 66282-1-PBS)

    Untreated and PNGase F-treated lysates of fetal human brain tissue and human spleen tissue were subjected to SDS PAGE followed by western blot with 66282-1-Ig (CD200 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. PNGase F was obtained from Atagenix (cat.NO. ata808). This data was developed using the same antibody clone with 66282-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66282-1-Ig (same clone as 66282-1-PBS)

    IHC staining of human tonsillitis using 66282-1-Ig (same clone as 66282-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66282-1-Ig (CD200 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66282-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66282-1-Ig (same clone as 66282-1-PBS)

    IHC staining of human tonsillitis using 66282-1-Ig (same clone as 66282-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66282-1-Ig (CD200 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66282-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

CD200 Monoclonal antibody, PBS Only

CD200 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66282-1-PBS

产品说明书

CloneNo. 5F3D6

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

CD200 molecule, MOX1, MOX2, MRC, OX 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

66282-1-PBS targets CD200 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag5045

Product name: Recombinant human CD200 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-269 aa of BC022522

Sequence: MERLVIRMPFCHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDREP

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 CD200 molecule
别名 CD200 molecule, MOX1, MOX2, MRC, OX 2
计算分子量 269 aa, 30 kDa
观测分子量 40-50 kDa
GenBank蛋白编号BC022522
基因名称 CD200
Gene ID (NCBI) 4345
RRIDAB_2881665
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP41217
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332).