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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98111-1-RR (same clone as 98111-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98111-1-RR (same clone as 98111-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD160 Rabbit Recombinant Antibody (98111-1-RR, Clone: 241415F2) (right) or 0.25 ug Isotype Control (left) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98111-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98111-1-RR

    Affinity and Kinetic Characterization of 98111-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98111-1-RR against Human CD160 were performed. The affinity constant is 1.81 nM.

Anti-Human CD160 Rabbit Recombinant Antibody, PBS Only

CD160 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98111-1-PBS

产品说明书

CloneNo. 241415F2

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

NK1, CD160 molecule, CD160 antigen, soluble form, CD160 antigen, BY55

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98111-1-PBS targets CD160 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD160 molecule
别名 NK1, CD160 molecule, CD160 antigen, soluble form, CD160 antigen, BY55
计算分子量 20 kDa
GenBank蛋白编号BC014465
基因名称 CD160
Gene ID (NCBI) 11126
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO95971
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD160 is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed on almost all intestinal intraepithelial lymphocytes (IELs), gamma delta T cells, CD56 (dim) CD16+ cytotoxic NK cells, and a minor subset of CD4+ and CD8+ T cells (PMID: 31332204; 25179432). The binding of CD160 to both classical and non-classical MHC I enhances NK and CD8+ cytotoxic T lymphocyte functions (PMID: 25179432). CD160 is a ligand for HVEM (herpes virus entry mediator) and the binding of CD160 to HVEM inhibits T cell activity (PMID: 19426226).