验证数据展示
产品信息
20006-1-PBS targets CD134/OX40 in WB, FC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, FC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | tumor necrosis factor receptor superfamily, member 4 |
| 别名 | TNFRSF4, ACT35, ACT35 antigen, CD134, OX40 |
| 计算分子量 | 29 kDa |
| 观测分子量 | 50-55 kDa, 40 kDa |
| GenBank蛋白编号 | NM_003327 |
| 基因名称 | CD134 |
| Gene ID (NCBI) | 7293 |
| RRID | AB_10733472 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P43489 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD134 (OX40) is a member of the TNFR-superfamily of receptors. Predominantly expressed on activated T cells, CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule. CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmunity (PMID: 26215166). CD134 can interact with TRAF2, TRAF3, and TRAF5.

