FITC Plus Anti-Mouse CD11b (M1/70)

CD11b Monoclonal Antibody for FC
Cat No. FITC-65055

产品说明书

CloneNo. M1/70

宿主/亚型

Rat / IgG2b, kappa

种属反应性

human, mouse

应用

FC and More (1)

CR3, CR3A, integrin alpha M, Itgam, Ly 40

缓冲液配方:  PBS and Azide
PBS and Azide
规格价格库存


经过测试的应用

Positive FC detected inmouse bone marrow cells, human PBMCs

推荐稀释比

应用推荐稀释比
Flow Cytometry (FC)FC : 0.25 ug per 10^6 cells in a 100 µl suspension
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

FITC-65055 targets CD11b in IF, FC applications and shows reactivity with human, mouse samples.

经测试应用 FC Application Description
文献引用应用IF, FC
经测试反应性 human, mouse
文献引用反应性human, mouse
免疫原

fusion protein

种属同源性预测
宿主/亚型 Rat / IgG2b, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 integrin alpha M
别名 CR3, CR3A, integrin alpha M, Itgam, Ly 40
计算分子量127 kDa
GenBank蛋白编号BC156991
基因名称 CD11b
Gene ID (NCBI) 16409
RRIDAB_2883745
偶联类型 FITC Plus Fluorescent Dye
最大激发/发射波长495 nm / 524 nm
形式Liquid
纯化方式Affinity purification
UNIPROT IDE9Q604
储存缓冲液 PBS with 0.09% sodium azide, pH 7.3.
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

实验方案

Product Specific Protocols
FC protocol for FITC Plus CD11b antibody FITC-65055Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle

Cell Chem Biol

Small-molecule MHC-II inducers promote immune detection and anti-cancer immunity via editing cancer metabolism

Authors - Ling Huang
mouseFC

Cell Commun Signal

Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage

Authors - Hanxiao Chang
mouseFC

Cell Death Discov

TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination

Authors - Qinmei Ma

Neoplasia

Tumor microenvironment(TME) and single-source dual-energy CT(ssDECT) on assessment of inconformity between RECIST1.1 and pathological remission in neoadjuvant immunotherapy of NSCLC

Authors - Chao Sun
mouseIF,FC

Int Immunopharmacol

Methionine enkephalin inhibited cervical carcinoma via apoptosis promotion and reduction of myeloid derived suppressor cell infiltrated in tumor.

Authors - Na Qu
mouseFC

Cell Death Dis

Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.

Authors - Hanyue Chang
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