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CCNL2 Polyclonal antibody

CCNL2 Polyclonal Antibody for WB, ELISA
Cat No. 11212-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

ANIA 6B, CCNL2, CCNM, cyclin L2, HCLA ISO, HLA ISO, PCEE, SB138

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inA375 cells, HeLa cells, U-251 cells, human placenta tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11212-1-AP targets CCNL2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 CCNL2 fusion protein Ag1710 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cyclin L2
别名 ANIA 6B, CCNL2, CCNM, cyclin L2, HCLA ISO, HLA ISO, PCEE, SB138
计算分子量 58 kDa
观测分子量 28 kDa
GenBank蛋白编号BC016333
基因名称 CCNL2
Gene ID (NCBI) 81669
RRIDAB_2073623
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96S94
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CCNL2 (Cyclin-L2) is also named as SB138 and Paneth cell-enhanced expression protein. Human cyclin L2 is a novel member of the cyclin family. Human cyclin L2 shares significant homology to cyclin L1, K, T1, T2, and C, which are involved in transcriptional regulation via phosphorylation of the C-terminal domain of RNA polymerase II (PMID: 14684736). Cyclin L2 co-localizes with splicing factors SC-35 and 9G8 within nuclear speckles and that it associates with hyperphosphorylated, but not hypophosphorylated, RNA polymerase II and CDK p110 PITSLRE kinase via its N-terminal cyclin domains (PMID: 14684736). Human cyclin L2 is expressed ubiquitously in normal human tissues and tumor cells.

实验方案

Product Specific Protocols
WB protocol for CCNL2 antibody 11212-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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