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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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验证数据展示

  • WB analysis using 84413-3-RR (same clone as 84413-3-PBS)

    WB analysis using 84413-3-RR (same clone as 84413-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84413-3-RR (CCL20/MIP-3 alpha antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84413-3-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 84413-3-RR (same clone as 84413-3-PBS)

    IHC staining of human colon using 84413-3-RR (same clone as 84413-3-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 84413-3-RR (CCL20/MIP-3 alpha antibody) at dilution of 1:2500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84413-3-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CCL20/MIP3A antibody included
  • IHC staining of human colon using 84413-3-RR (same clone as 84413-3-PBS)

    IHC staining of human colon using 84413-3-RR (same clone as 84413-3-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 84413-3-RR (CCL20/MIP-3 alpha antibody) at dilution of 1:2500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84413-3-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CCL20/MIP3A antibody included

CCL20/MIP-3 alpha Recombinant antibody, PBS Only

CCL20/MIP-3 alpha Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 84413-3-PBS

产品说明书

CloneNo. 241694B4

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

CCL20, MIP-3 Alpha, MIP-3α, 241694B4, Beta-chemokine exodus-1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy CCL20/MIP3A Ready-To-Use IHC Kit. CCL20/MIP3A primary antibody included.

产品信息

84413-3-PBS targets CCL20/MIP-3 alpha in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 CCL20/MIP-3 alpha fusion protein Eg2398 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chemokine (C-C motif) ligand 20
别名 CCL20, MIP-3 Alpha, MIP-3α, 241694B4, Beta-chemokine exodus-1
计算分子量11kDa
观测分子量11 kDa
GenBank蛋白编号NM_004591.3
基因名称 CCL20/MIP-3 alpha
Gene ID (NCBI) 6364
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP78556-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.