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验证数据展示

  • IHC staining of human lung cancer using 22293-1-AP (same clone as 22293-1-PBS)

    IHC staining of human lung cancer using 22293-1-AP (same clone as 22293-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 22293-1-AP (CC2D2A Antibody) at dilution of 1:50(under 10x lens). This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 22293-1-AP (same clone as 22293-1-PBS)

    IHC staining of human lung cancer using 22293-1-AP (same clone as 22293-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 22293-1-AP (CC2D2A Antibody) at dilution of 1:50(under 40x lens). This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

  • IF Staining of hTERT-RPE1 cells using 22293-1-AP (same clone as 22293-1-PBS)

    IF Staining of hTERT-RPE1 cells using 22293-1-AP (same clone as 22293-1-PBS)

    IF result (strong nucleus and the base stain) of anti-CC2D2A (22293-1-AP, 1:50) with serum-starved hTERT-RPE1 (MeOH fixed) by Dr. Moshe Kim. This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

  • WB analysis using 22293-1-AP (same clone as 22293-1-PBS)

    WB analysis using 22293-1-AP (same clone as 22293-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22293-1-AP (CC2D2A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

CC2D2A Polyclonal antibody, PBS Only

CC2D2A Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 22293-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

22293-1-PBS targets CC2D2A in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 coiled-coil and C2 domain containing 2A
别名
计算分子量 186 kDa
观测分子量 190 kDa
GenBank蛋白编号NM_020785
基因名称 CC2D2A
Gene ID (NCBI) 57545
RRIDAB_2879063
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9P2K1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CC2D2A, also named as KIAA1345, may be involved in cilia formation. CC2D2A encodes a protein with similar overall structure to RPGRIP1L, including coiled-coil domains, a C2 domain, and an overlapping centrosomal protein-related domain. CC2D2A physically interacts with CEP290, and loss of Cc2d2a function in the zebrafish sentinel mutant results in abnormal body shape and pronephric (kidney) cysts that is strongly exacerbated by knockdown of Cep290 function. (PMID:19778711 )Defects in CC2D2A are the cause of Meckel syndrome type 6 (MKS6). Defects in CC2D2A are the cause of Joubert syndrome type 9 (JBTS9). The antibody is specific to CC2D2A.

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