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×
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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68452-1-Ig (same clone as 68452-1-PBS)

    WB analysis using 68452-1-Ig (same clone as 68452-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68452-1-Ig (CAMK4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68452-1-PBS in a different storage buffer formulation.

CAMK4 Monoclonal antibody, PBS Only

CAMK4 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68452-1-PBS

产品说明书

CloneNo. 1G7A7

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse, rat

应用

WB, Indirect ELISA

别名

CaM kinase GR, CaMK GR, CaMK IV, CAMK4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

68452-1-PBS targets CAMK4 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse, rat
免疫原

CatNo: Ag33332

Product name: Recombinant human CAMK4 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-302 aa of BC025687

Sequence: MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTG

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 calcium/calmodulin-dependent protein kinase IV
别名 CaM kinase GR, CaMK GR, CaMK IV, CAMK4
计算分子量 473 aa, 52 kDa
观测分子量56-65 kDa
GenBank蛋白编号BC025687
基因名称 CAMK4
Gene ID (NCBI) 814
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ16566
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CaMK4 (Calcium/calmodulin-dependent protein kinase IV) is a multifunctional serine/threonine kinase that regulates gene expression by activating transcription factors in a wide range of immune cells including T cells and antigen-presenting cells. The function of CaMK4 is suggested to be abnormal mainly in systemic lupus erythematosus (SLE), which is characterized by autoantibody production, immune complex formation, and immune dysregulation (PMID: 29252071). CaMKIV can translocate between the nucleus and cytoplasm (PMID: 21301225)