CACNA1S Polyclonal antibody

CACNA1S Polyclonal Antibody for WB, IHC, ELISA
Cat No. 22279-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA

CACH1, CACN1, CACNL1A3, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Cav1.1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive WB detected inhuman brain tissue, mouse kidney tissue, rat kidney tissue
Positive IHC detected inhuman skeletal muscle tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

22279-1-AP targets CACNA1S in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IHC
经测试反应性 human, mouse, rat
文献引用反应性human
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 calcium channel, voltage-dependent, L type, alpha 1S subunit
别名 CACH1, CACN1, CACNL1A3, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Cav1.1
计算分子量 212 kDa
观测分子量 200-220 kDa
GenBank蛋白编号NM_000069
基因名称 CACNA1S
Gene ID (NCBI) 779
RRIDAB_2879058
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ13698
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CACNA1S, also named as CACH1, CACN1 and CACNL1A3, belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family and CACNA1S subfamily. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. CACNA1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. The antibody is specific to CACNA1S.

实验方案

Product Specific Protocols
WB protocol for CACNA1S antibody 22279-1-APDownload protocol
IHC protocol for CACNA1S antibody 22279-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Reproduction

Deep RNA sequencing analysis of syncytialization-related genes during BeWo cell fusion.

Authors - Ru Zheng
humanWB

bioRxiv

Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM

Authors - Jorge L Jimenez-Macias
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