CACNA1H Polyclonal antibody

CACNA1H Polyclonal Antibody for WB, ELISA
Cat No. 28092-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

CACNA1HB, Cav3.2, EIG6, FLJ90484, Low-voltage-activated calcium channel alpha1 3.2 subunit

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

28092-1-AP targets CACNA1H in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 CACNA1H fusion protein Ag26094 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 calcium channel, voltage-dependent, T type, alpha 1H subunit
别名 CACNA1HB, Cav3.2, EIG6, FLJ90484, Low-voltage-activated calcium channel alpha1 3.2 subunit
计算分子量 259 kDa
观测分子量259 kDa
GenBank蛋白编号NM_001005407
基因名称 CACNA1H
Gene ID (NCBI) 8912
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO95180
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Voltage-dependent T-type calcium channel subunit alpha-1H (CACNA1H) is located in the plasma membrane of various tissues, including the brain cortex, amygdala, caudate nucleus, putamen, kidney, liver, and heart. This subunit regulates muscle contraction, secretion, neurotransmission, and gene expression by forming the pore (PMID: 33985586). Predominantly, the changes observed are missense mutations associated with gain-of-function, resulting in an increased influx of calcium into adrenal cells (PMID: 33985586; 37311830).

实验方案

Product Specific Protocols
WB protocol for CACNA1H antibody 28092-1-APDownload protocol
Standard Protocols
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