×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of human placenta using 84890-4-RR (same clone as 84890-4-PBS)

    WB analysis of human placenta using 84890-4-RR (same clone as 84890-4-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 84890-4-RR (C9 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84890-4-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 84890-4-RR (same clone as 84890-4-PBS)

    IHC staining of human colon using 84890-4-RR (same clone as 84890-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 84890-4-RR (C9 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84890-4-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 84890-4-RR (same clone as 84890-4-PBS)

    IHC staining of human tonsillitis using 84890-4-RR (same clone as 84890-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84890-4-RR (C9 antibody) at dilution of 1:4000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84890-4-PBS in a different storage buffer formulation.

  • Affinity of 84890-4-RR

    Affinity of 84890-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84890-4-RR against Human C9 were performed. The affinity constant is 0.739 nM.

C9 Recombinant monoclonal antibody, PBS Only

C9 Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 84890-4-PBS

产品说明书

CloneNo. 242475B11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

Complement C9, complement component 9, Complement component C9, Complement component C9a, Complement component C9b

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

84890-4-PBS targets C9 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Eg1282

Product name: Recombinant Human Component C9 protein (His Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-6*HIS

Domain: 22-559 aa of NM_001737.4

Sequence: QYTTSYDPELTESSGSASHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGDRRQCVPTEPCEDAEDDCGNDFQCSTGRCIKMRLRCNGDNDCGDFSDEDDCESEPRPPCRDRVVEESELARTAGYGINILGMDPLSTPFDNEFYNGLCNRDRDGNTLTYYRRPWNVASLIYETKGEKNFRTEHYEEQIEAFKSIIQEKTSNFNAAISLKFTPTETNKAEQCCEETASSISLHGKGSFRFSYSKNETYQLFLSYSSKKEKMFLHVKGEIHLGRFVMRNRDVVLTTTFVDDIKALPTTYEKGEYFAFLETYGTHYSSSGSLGGLYELIYVLDKASMKRKGVELKDIKRCLGYHLDVSLAFSEISVGAEFNKDDCVKRGEGRAVNITSENLIDDVVSLIRGGTRKYAFELKEKLLRGTVIDVTDFVNWASSINDAPVLISQKLSPIYNLVPVKMKNAHLKKQNLERAIEDYINEFSVRKCHTCQNGGTVILMDGKCLCACPFKFEGIACEISKQKISEGLPALEFPNEK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 complement component 9
别名 Complement C9, complement component 9, Complement component C9, Complement component C9a, Complement component C9b
计算分子量63kDa
观测分子量64 kDa
GenBank蛋白编号NM_001737.4
基因名称 C9
Gene ID (NCBI) 735
RRIDAB_3743814
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDP02748
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The final consequence of complement activation is the formation of the membrane attack complex (MAC), a multiprotein assembly that perforates cell membranes, forming transmembrane channels. The MAC plays a critical role in complement-mediated hemolysis and inflammasome activation (PMID: 27444648). Complement component 9 (C9) is 1 of 5 late-acting proteins of complement that participate in the assembly and function of the MAC. C9 may be cleaved by thrombin to generate fragments C9a (25 kDa) and C9b (37 kDa) (PMID: 7523406).

||
New chat

Able™

正在加载，请稍候...