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验证数据展示

  • WB analysis using 85652-1-RR (same clone as 85652-1-PBS)

    WB analysis using 85652-1-RR (same clone as 85652-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85652-1-RR (C8G antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85652-1-PBS in a different storage buffer formulation.

  • WB analysis of human plasma using 85652-1-RR (same clone as 85652-1-PBS)

    WB analysis of human plasma using 85652-1-RR (same clone as 85652-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 85652-1-RR (C8G antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85652-1-PBS in a different storage buffer formulation.

C8G Recombinant monoclonal antibody, PBS Only

C8G Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 85652-1-PBS

产品说明书

CloneNo. 242479G11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

C8C

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85652-1-PBS targets C8G in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag18261

Product name: Recombinant human C8G protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-202 aa of BC113626

Sequence: MLPPGTATLLTLLLAAGSLGQKPQRPRRPASPISTIQPKANFDAQQFAGTWLLVAVGSACRFLQEQGHRAEATTLHVAPQGTAMAVSTFRKLDGICWQVRQLYGDTGVLGRFLLQARGARGAVNVVVAETDYQSFAVLYLERAGQLSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIFYFPKYGFCEAADQFHVLDEVRR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 complement component 8, gamma polypeptide
别名 C8C
计算分子量 202 aa, 22 kDa
观测分子量18-22 kDa
GenBank蛋白编号BC113626
基因名称 C8G
Gene ID (NCBI) 733
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP07360
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The gamma chain of complement component 8 (C8G) is one of three different subunits (alpha, beta, and gamma) of the eighth complement component (C8), which is a component of the MAC (membrane attack complex) (PMID:33382892). Although the roles of C8A and C8B are directly associated with MAC formation, C8G is not essential in the assembly and activity of the MAC (PMID:11960635). Moreover, C8G was shown to inhibit neuroinflammation by interfering with the sphingosine-1-phosphate (S1P)-S1PR2 interaction (PMID:34149451).

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