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验证数据展示

  • WB analysis using 17346-1-AP (same clone as 17346-1-PBS)

    WB analysis using 17346-1-AP (same clone as 17346-1-PBS)

    human plasma was subjected to SDS PAGE followed by western blot with 17346-1-AP (C1r antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17346-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 17346-1-AP (same clone as 17346-1-PBS)

    IHC staining of human liver using 17346-1-AP (same clone as 17346-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 17346-1-AP (C1r Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 17346-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with C1R antibody included
  • IHC staining of human liver using 17346-1-AP (same clone as 17346-1-PBS)

    IHC staining of human liver using 17346-1-AP (same clone as 17346-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 17346-1-AP (C1R Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 17346-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with C1R antibody included

C1r Polyclonal antibody, PBS Only

C1r Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 17346-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

Complement C1r, Complement C1r subcomponent, Complement C1r subcomponent heavy chain, Complement C1r subcomponent light chain, EC:3.4.21.41

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy C1R Ready-To-Use IHC Kit. C1R primary antibody included.

产品信息

17346-1-PBS targets C1r in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag11390

Product name: Recombinant human C1R protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 356-705 aa of BC035220

Sequence: AVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIKKEMEEED

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 complement component 1, r subcomponent
别名 Complement C1r, Complement C1r subcomponent, Complement C1r subcomponent heavy chain, Complement C1r subcomponent light chain, EC:3.4.21.41
计算分子量 705 aa, 80 kDa
观测分子量 85 kDa, 30 kDa
GenBank蛋白编号BC035220
基因名称 C1R
Gene ID (NCBI) 715
RRIDAB_2878392
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP00736
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein that can be cleaved into an A chain and a B chain upon activation. This antibody recognizes the full-length C1r chain and the cleaved B chain.

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