验证数据展示
经过测试的应用
| Positive WB detected in | A549 cells, U-251 cells, mouse liver tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
32933-1-AP targets C14orf73 in applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag35995 Product name: Recombinant human C14orf73 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-255 aa of BC113655 Sequence: MPSPQTDTPGPELQSPKEAEEPQTPAQGSRRTSSRKEPNAHRKDGTRLGLGSLRQAFSRASQRALTQVSKEDTGLFWRSSCSLFRSFRQALNEGPATGHSQATPEVPSGVMNGVSQQASTGAASEELKPEAEGKSVADLITERQLLAAFEQLLRLETLLVAEKASRTFEQDPTAFARRAMDVCLHYDGLAAEIGAIVRETLDSDGVDAAALAELARVVSAEEEAHPSPPDDGDFLRTPRRWRQHWEEAVRRSAQE 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chromosome 14 open reading frame 73 |
| 别名 | EXOC3L4, Exocyst complex component 3-like protein 4 |
| 观测分子量 | 80 kDa |
| GenBank蛋白编号 | BC113655 |
| 基因名称 | C14orf73 |
| Gene ID (NCBI) | 91828 |
| RRID | AB_3742795 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q17RC7 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
C14orf73 (chromosome 14 open reading frame 73), also known as EXOC3L4 or SEC6-like protein C14orf73, is a protein composed of 722 amino acids and belongs to the SEC6 family. This protein is a component of the exocyst complex, which plays an important role in the cellular secretion process, participating in vesicle targeting and fusion. The C14orf73 protein is predicted to have SNARE binding activity, involved in the localization of the exocyst complex and exocytosis. Additionally, rare variants in the splicing regulatory elements of this gene are associated with Alzheimer's disease.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for C14orf73 antibody 32933-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
