验证数据展示
产品信息
33627-1-PBS targets C10orf76 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag38164 Product name: Recombinant human C10orf76 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 539-689 aa of NM_024541.2 Sequence: DTFLPTPSSYDELYYEIIRMHQSFDNLYSMVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQDGLDQYERYSEQHKEAAFFKELVRSISTNVRRNLAFHTLSQEVLLKEFSTIS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chromosome 10 open reading frame 76 |
| 别名 | Armadillo-like helical domain-containing protein 3, ARMH3 |
| 计算分子量 | 79kDa，689aa |
| 观测分子量 | 70-79 kDa |
| GenBank蛋白编号 | NM_024541.2 |
| 基因名称 | C10orf76 |
| Gene ID (NCBI) | 79591 |
| RRID | AB_3743033 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q5T2E6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
C10orf76, also known as ARMH3 (Armadillo-like helical domain-containing protein 3), was previously reported to be a regulator of phosphatidylinositol 4-kinase beta (PI4KB, also known as PI4KIIIbeta) at the TGN. Upon cGAMP-triggered translocation, ARMH3 interacted with STING at the Golgi and recruited phosphatidylinositol 4-kinase beta (PI4KB) to synthesize PI4P, which directed STING Golgi-to-endosome trafficking via PI4P-binding proteins AP-1 and GGA2 (PMID: 39580461, 36921576).
