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验证数据展示

  • WB analysis of PC-3 using 14134-1-AP (same clone as 14134-1-PBS)

    WB analysis of PC-3 using 14134-1-AP (same clone as 14134-1-PBS)

    PC-3 cells were subjected to SDS PAGE followed by western blot with 14134-1-AP (β-ENaC antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14134-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 14134-1-AP (same clone as 14134-1-PBS)

    IHC staining of human kidney using 14134-1-AP (same clone as 14134-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14134-1-AP (β-ENaC Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 14134-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 14134-1-AP (same clone as 14134-1-PBS)

    IHC staining of human kidney using 14134-1-AP (same clone as 14134-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14134-1-AP (β-ENaC Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 14134-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

Beta ENaC Polyclonal antibody, PBS Only

Beta ENaC Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 14134-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

14134-1-PBS targets Beta ENaC in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag5348

Product name: Recombinant human β-ENaC protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 68-401 aa of BC036352

Sequence: GIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNC

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sodium channel, nonvoltage-gated 1, beta
别名
计算分子量 640 aa, 73 kDa
观测分子量 75-80 kDa
GenBank蛋白编号BC036352
基因名称 Beta ENaC
Gene ID (NCBI) 6338
RRIDAB_2184378
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP51168
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SCNN1B, also named as SCNEB, ENaCB, Beta-NaCH and Beta-ENaC, belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family and SCNN1B subfamily. Sodium permeable non-voltage-sensitive ion channel is inhibited by the diuretic amiloride. SCNN1B mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. It controls the reabsorption of sodium in kidney, colon, lung and sweat glands. SCNN1B plays a role in taste perception.

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