BTG1 Polyclonal antibody

BTG1 Polyclonal Antibody for IHC, ELISA
Cat No. 14879-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, ELISA and More (3)

BTG1, Protein BTG1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive IHC detected inhuman thyroid cancer tissue, human lymphoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

14879-1-AP targets BTG1 in WB, IHC, IF, ELISA, ICC-IF applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, ELISA Application Description
文献引用应用WB, IHC, IF, ICC-IF
经测试反应性 human, mouse, rat
文献引用反应性human, mouse
免疫原 BTG1 fusion protein Ag6651 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 B-cell translocation gene 1, anti-proliferative
别名 BTG1, Protein BTG1
计算分子量 19 kDa
GenBank蛋白编号BC064953
基因名称 BTG1
Gene ID (NCBI) 694
RRIDAB_2067644
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP62324
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BTG1 is a member of the TOB/BTG family of proteins known to inhibit cell proliferation and negatively regulate the cell cycle (PMID: 25017022). It is strongly expressed in quiescent cells (maximal in the G0/G1 phase) and down-regulated as the cells enter the growth cycle (PMID: 1373383). BTG1 protein is localized in cytoplasm and nucleus, and can interact with CAF1 and PRMT1 (PMID: 1113675, 9712883, 26622543). The aberration of BTG1 expression is associated with B-cell lymphocytic leukemia, and may serve as a diagnostic indicator and prognostic marker of thyroid carcinoma (PMID: 2069907, 25017022).

实验方案

Product Specific Protocols
IHC protocol for BTG1 antibody 14879-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
HUMANWB,IHC

Oncotarget

BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy.

Authors - Hua-chuan Zheng
humanIHC

Front Oncol

BTG1 Overexpression Might Promote Invasion and Metastasis of Colorectal Cancer via Decreasing Adhesion and Inducing Epithelial-Mesenchymal Transition.

Authors - Shuang Zhao
humanIHC

Front Oncol

Development and validation of a combined hypoxia and ferroptosis prognostic signature for breast cancer

Authors - Jianxin Zhong

Int J Mol Sci

BTG1 expression correlates with the pathogenesis and progression of ovarian carcinomas.

Authors - Yang Zhao
human,mouseWB,IF

J Cell Physiol

Long noncoding RNA DGCR5 suppresses gastric cancer progression by acting as a competing endogenous RNA of PTEN and BTG1.

Authors - Ying Xu
humanWB

Mol Med Rep

Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA

Authors - QIANG CHENG
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