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验证数据展示

  • IHC staining of human breast cancer using 28016-1-AP (same clone as 28016-1-PBS)

    IHC staining of human breast cancer using 28016-1-AP (same clone as 28016-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 28016-1-AP (BPTF antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28016-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BPTF antibody included
  • IF Staining of HepG2 using 28016-1-AP (same clone as 28016-1-PBS)

    IF Staining of HepG2 using 28016-1-AP (same clone as 28016-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using BPTF antibody (28016-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 28016-1-PBS in a different storage buffer formulation.

BPTF Polyclonal antibody, PBS Only

BPTF Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 28016-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, IF/ICC, Indirect ELISA

别名

FAC1, FALZ

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy BPTF Ready-To-Use IHC Kit. BPTF primary antibody included.

产品信息

28016-1-PBS targets BPTF in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag27761

Product name: Recombinant human BPTF protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 459-657 aa of NM_004459

Sequence: MEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTNATSEETSPSEGRSP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 bromodomain PHD finger transcription factor
别名 FAC1, FALZ
计算分子量 338 kDa
GenBank蛋白编号NM_004459
基因名称 BPTF
Gene ID (NCBI) 2186
RRIDAB_2918139
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ12830
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Bromodomain PHD finger transcription factor (BPTF), a histone-binding component of NURF (nucleosome-remodeling factor), plays an important role in catalyzing ATP-dependent nucleosome sliding and facilitating transcription of chromatin. It has been reported that BPTF maybe a novel and potential therapeutic target in hepatocellular carcinoma. BPTF may also regulate transcription through direct binding to DNA or transcription factors.(PMID: 30419422)

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