BICD2 Polyclonal antibody

BICD2 Polyclonal Antibody for WB, ELISA
Cat No. 29603-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

Human

应用

WB, ELISA

bA526D8.1, Bic D 2, BICD2, KIAA0699, Protein bicaudal D homolog 2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inA549 cells, Hela cells, Jurkat cells, K-562 cells, MCF-7 cells
Planning an IHC experiment? We recommend our IHCeasy BICD2 Ready-To-Use IHC Kit. BICD2 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

29603-1-AP targets BICD2 in WB, ELISA applications and shows reactivity with Human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human
免疫原 BICD2 fusion protein Ag31279 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 bicaudal D homolog 2 (Drosophila)
别名 bA526D8.1, Bic D 2, BICD2, KIAA0699, Protein bicaudal D homolog 2
计算分子量 855 aa, 97 kDa
观测分子量93-96 kDa
GenBank蛋白编号BC073970
基因名称 BICD2
Gene ID (NCBI) 23299
RRIDAB_2935474
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8TD16
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Protein bicaudal D homolog 2 (BICD2) acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623).

实验方案

Product Specific Protocols
WB protocol for BICD2 antibody 29603-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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