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BICD2 Polyclonal antibody

BICD2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 29603-1-AP

Print datasheet

Synonyms

bA526D8.1, Bic D 2, BICD2, KIAA0699, Protein bicaudal D homolog 2

验证数据展示

  • WB analysis using 29603-1-AP

    WB analysis using 29603-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 29603-1-AP (BICD2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inA549 cells, Hela cells, Jurkat cells, K-562 cells, MCF-7 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

29603-1-AP targets BICD2 in WB, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA
Tested Reactivity Human
Immunogen BICD2 fusion protein Ag31279 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name bicaudal D homolog 2 (Drosophila)
Synonyms bA526D8.1, Bic D 2, BICD2, KIAA0699, Protein bicaudal D homolog 2
Calculated Molecular Weight 855 aa, 97 kDa
Observed Molecular Weight93-96 kDa
GenBank Accession NumberBC073970
Gene Symbol BICD2
Gene ID (NCBI) 23299
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8TD16
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Protein bicaudal D homolog 2 (BICD2) acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623).

实验方案

Product Specific Protocols
WB protocol for BICD2 antibody 29603-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols